Clearly the whole thing got out of control, but I have to say Jacobson was on to something. IF USED CORRECTLY, amphetamines cause an overall performance enhancing effect in the majority of people, and are rather benign. Methamphetamine is neurotoxic in high doses but dextroamphetamine is not. Proper usage of dextroamphetamine (ie, dose, frequency, roa) very often is an excellent, truly helpful and effective medication...not only those with "ADD." PROPER usage. 5-120mg a day depending on several factors. More than 120, even in the most extreme cases, imo is unwarranted. 20-60mg seems to be the average sweet spot for the majority. "Drugs" and human beings have always been connected. Its about using them the correct way...the negative press is due to PEOPLE and their inability to moderate, not the drugs. The more we as a society can take off the blinders about substances, the closer we get to living symbiotically with these performance enhancing, pain relieving, mind expanding, etc substances. The prohibitionist attitude of the last hundred years has proven that the human/drug relationship WILL NEVER GO AWAY, NOR SHOULD IT. We can learn and grow with the use of drugs. Or we can destroy ourselves with them. This anachronistic, infantile, unscientific approach to substances is one of the sadder realities of modern human life. Hopefully its not long for this world. Truth can't be held down forever, it'll always find a way out.